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糖尿病为什么会让皮肤坏死?
发布时间:2011-03-28 11:34     来源:君健网

    一位妇女双小腿皮肤经常起红斑、丘疹,而且易出现溃疡,对症治疗,始终不愈。后住院进行全面检查,发现有糖尿病,进行治疗,血糖控制后,局部对症治疗,皮损消退,至今未复发。原来该妇女患有糖尿病性皮肤病——类脂质渐进性皮肤坏死。

    糖尿病患者之所以会出现类脂质渐进性皮肤坏死,主要是由于糖尿病引起了微血管病,糖蛋白在小血管壁沉积,逐渐引起血管闭塞、组织坏死。

    类脂质渐进性皮肤坏死的临床表现主要为两小腿胫前、大腿、踝部、足部出现不规则圆或卵圆形硬皮病样斑块,边缘清楚,表面光滑呈釉状,中央凹陷呈硫磺色,构成硬的黄色斑块,外围呈紫红或淡红色。在黄色部位有无数毛细血管扩张和小而深色的斑,常有鳞屑或结痂。约1/3病例可在红斑基础上发生溃疡。

    类脂质渐进性皮肤坏死的治疗糖尿病患者必须有效地控制糖尿病,但即使糖尿病被控制后,皮损也不能完全消退,仅有不同程度的改善。对皮肤病变主要是采取对症治疗,同时可加服一些活血化瘀、改善微循环的药物,如口服复方丹参片和维生素e。还需注意避免小腿外伤及长时间站立,有条件者最好抬高双下肢,并注意防寒保暖。

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