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中国自身免疫性疾病患率增加 专家吁红斑狼疮更名
发布时间:2011-05-13 11:41     来源:君健网
    记者今日获悉,目前,中国内地自身免疫性疾病患病率呈上升趋势。上海风湿学会主任委员、华山医院副院长邹和建表示,精神、心理因素以及环境因素都可能诱发此类疾病。

  第十一届自身免疫与自身抗体国际会议(IWAA)12日在上海举行,这也是IWAA会议首次在中国举行。“自身抗体之父”美国类风湿病学院大师、IWAA会议创始人Eng M. Tan教授以及数十位世界顶尖专家会聚申城进行高水平学术交流。

  本届IWAA大会主席——上海市风湿病临床医学中心主任陈顺乐表示,大会首次将生物制剂靶向治疗引入议程,与自身免疫原理和自身抗体一起对发病机理到临床诊断和理疗做全方位阐述,将进一步提高中国及全球自身免疫性疾病的诊疗水平。

  据悉,自身免疫性疾病是指机体对自身抗原发生免疫反应而导致自身组织损害所引起的疾病。系统性红斑狼疮、类风湿关节炎等均为典型代表。

  上海风湿学会主任委员邹和建告诉记者,近年来自身免疫性疾病患病率上升原因不仅在诊断水平的提高,环境因素、心理压力增大也大大增加了人们罹患此类疾病的几率。他说,已有研究证明某些环境物质是诱发自身免疫性疾病的重要因素。

  上海风湿病研究所负责人沈南在接受采访时强调了遗传因素在自身免疫性疾病发病中的作用。他指出,随着人类基因组分析技术的发展,在很短时间内区分患者及正常人在基因方面的差异也是近年来相关研究的重要进展。他说,遗传学的深入研究将有助于进一步探究此类疾病发病机理和找到易患标志。

  对于首次引入亦称的生物制剂靶向治疗,陈顺乐说,近十年来,对自身免疫性疾病的重要研究进展就是将生物制剂靶向治疗用于临床,使得治疗效果和针对性显著提高。

  另据记者了解,目前中国有一百万系统性红斑狼疮患者,虽然8成患者经过及时有效治疗,能够和健康人一样学习、工作、结婚、生育。但是人们的认识仍存在误区,患者仍有压力和恐惧。对此,陈顺乐呼吁全社会更加关注红斑狼疮患者心理健康,增强患者的社会心理支持,希望将该病的名称改为“蝴蝶病”。

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